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The associations between various risk factors and melanoma have been shown in other studies (eMethod 2 in the Supplement).20- 24 Information on these factors was collected in the questionnaires, including the number of moles at least 3 mm in diameter on the arms (1987); natural hair color at age 18 years (1988); and state of residence at birth and age 15 and 30 years, lifetime numbers of blistering sunburns, and adolescent tendency to sunburn (1992). According to the state of residence, the UV index at birth and age 15 and 30 years was categorized into 3 categories (≤5, 6, or ≥7). Family history of melanoma in first-degree relatives was asked about in 1990 and 1992. In 2008, sun exposure in the middle of the day during summer (10 am to 3 pm) was inquired about for high school/college age and age 25 to 35, 36 to 59, and 60 years or older. Information on smoking, body mass index, and physical activity was collected biennially. can levitra be cut in half There is limited clinical data on the safety of single-dose administration of CIALIS in patients with severe hepatic insufficiency (Child-Pugh Class C). If CIALIS is prescribed, a careful individual benefit/risk evaluation should be undertaken by the prescribing physician.

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