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In each of these trials, conducted without regard to the timing of dose and sexual intercourse, Cialis demonstrated clinically meaningful and statistically significant improvement in erectile function, as measured by the EF domain of the IIEF questionnaire and Questions 2 and 3 of the SEP diary (see Table 17). When taken as directed, Cialis was effective at improving erectile function.5) Michael Douglas: Back in 2005, Douglas shared his praise for the blue pill for helping bridge the 25-year age gap with his wife, Catherine Zeta-Jones. "God bless her that she likes older guys," he told the Daily Mail. "And some wonderful enhancements have happened in the last few years—Viagra, Cialis—that can make us all feel younger," he said. The couple would split in 2013 but have been spotted together on multiple occassions sparking reconciliation rumors. Douglas has even been caught wearing his wedding ring.