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In the major North American fixed-dose trial, 762 patients (mean age 57, range 20-83 years; 79% White, 13% Black, 4% Hispanic, 2% Asian and 2% Other) were evaluated. The mean baseline EF Domain scores were 13, 13, 13, 14 for the Levitra 5 mg, 10 mg, 20 mg and placebo groups, respectively. There was significant improvement (p <0.0001) at 3 months with Levitra (EF Domain scores of 18, 21, 21, for the 5 mg, 10 mg, and 20 mg dose groups, respectively) compared to the placebo group (EF Domain score of 15). The European trial (total N=803) confirmed these results. The improvement in mean score was maintained at all doses at 6 months in the North American trial.Get emergency medical help if you have signs of an allergic reaction to Viagra: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Usually the recommended dose is 50 mg. It is taken approximately 0,5-1 hour before sexual activity. Do not take Viagra more then once a day.
sickle cell anaemia (an abnormality of red blood cells) generic viagra sildenafil Have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia. The frequency of patients reporting improvement of erections in response to a global question in four of the randomized, double-blind, parallel, placebo-controlled fixed dose studies (1797 patients) of 12 to 24 weeks duration is shown in Figure 7. These patients had erectile dysfunction at baseline that was characterized by median categorical scores of 2 (a few times) on principal IIEF questions. Erectile dysfunction was attributed to organic (58%; generally not characterized, but including diabetes and excluding spinal cord injury), psychogenic (17%), or mixed (24%) etiologies. Sixty-three percent, 74%, and 82% of the patients on 25 mg, 50 mg and 100 mg of Viagra, respectively, reported an improvement in their erections, compared to 24% on placebo. In the titration studies (n=644) (with most patients eventually receiving 100 mg), results were similar.
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Prolonged Erection and Priapism cialis stories One of the less common side effects associated with Viagra is a medical emergency known as priapism. Priapism is a painful erection lasting for more than four hours which requires immediate medical attention and treatment. Priapism may lead to permanent damage if left untreated, including the permanent loss of ability to have an erection. Levitra acts similarly to Viagra regarding possible side effects and onset and duration of pharmacologic action. However, Levitra is available at a lower dose and commonly causes dizziness. The typical recommended starting dose of Levitra is 10 mg and dosages can range from 5 mg to 20 mg depending on desired response and adverse reactions. Cialis differs from both Viagra and Levitra with regard to onset and duration of action. With treatment with Cialis, improvement in erectile function is possible for anywhere from 24 to 36 hours after administration of a dose, significantly longer than with Viagra. In addition, Cialis typically has a quicker onset of action and begins to work within approximately 30 minutes. Similar to Levitra, the recommended starting dose for Cialis, as needed, is 10 mg. Doses may range from 5 mg to 20 mg depending on efficacy and patient tolerability.
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